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He also worked as a voice actor in the animated films Despicable Me in 2010, Hop in 2011, and Despicable Me 2 in 2013, and played the title character of the 2011 remake of the romantic comedy Arthur.
When Brand was 8, his mother contracted uterine cancer and then breast cancer one year later.
While she underwent treatment, Brand lived with relatives. When he was 16, he left home because of disagreements with his mother's partner.
Brand then started to use illegal drugs such as cannabis, amphetamines, LSD, and ecstasy.
He presented Dancefloor Chart, touring nightclubs in Britain and Ibiza, and hosted the tea-time request show Select.
Brand was fired several days after coming to work dressed as Osama bin Laden the day after the 11 September 2001 attacks and bringing his drug dealer to the MTV studios.
Since guest editing an edition of British political weekly New Statesman in 2013, Brand has become known as a public activist and campaigner, and has spoken on a wide range of political and cultural issues, including wealth inequality, addiction, corporate capitalism, climate change, and media bias.